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Fig. 1 | Genome Medicine

Fig. 1

From: Microbiota of the prostate tumor environment investigated by whole-transcriptome profiling

Fig. 1

Differences in overall alpha diversity between benign and malignant tissue samples as measured using six different measures of alpha diversity for the discovery (A) and validation (B) cohorts. Observed, Chao1, and ACE capture aspects of species richness, whereas Shannon, Simpson, and Inverse Simpson capture both species richness and evenness. A Wilcoxon rank sum test was used to compare the diversity estimates between the two groups. Compared to the benign, malignant tissue samples showed an overall reduction in the species diversity in the discovery cohort which was significant at a p value cut-off of 0.05. While this trend was also observed in the validation cohort, the p values did not reach statistical significance for some of the diversity estimates. ns not significant

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