Fig. 2From: Somatic mutational profiles and germline polygenic risk scores in human cancerCorrelations between somatic mutation counts and age at cancer diagnosis for each cancer type. Only the correlations with age at cancer diagnosis for those cancer-signature pairs included in the analyses are shown in this figure. The number in each cell and the cell color represent the Spearman correlation (ρ) between mutation counts of a SBS signature or TSMC (y-axis) and age at diagnosis in a cancer type (x-axis). Corrections passed the Bonferroni threshold (p < 0.05/69 = 7.25 × 10-4) are marked with triple asterisk (***), correlations with p < 0.01 are marked with double asterisk (**), and correlations with p < 0.05 are marked with single asterisk (*)Back to article page