Fig. 2

Relationships between the mutation-based gene set and other characteristics. A Univariate and multivariate Cox regression analyses of the mutation-based gene set in the training cohort. B Univariate and multivariate Cox regression analyses of the mutation-based gene set in the validation cohort. C Comparison of C-indexes between the mutation-based gene set and the TMB and drug type in the training cohort. Error bars represent the 95% CI of the C-index. D Comparison of C-indexes between the mutation-based gene set and the TMB and drug type in the validation cohort. E Nomogram for predicting survival probability at 12 and 24 months in the Riaz cohort. F Calibration curves for evaluating the predictive accuracy of the nomogram in the Riaz cohort. The gray line represents ideal performance. The purple line represents actual performance