Fig. 5

Association of baseline gut microbiota composition with weight loss. A higher abundance of the genus Dorea at baseline may be associated with a difficulty in losing excess weight. a Volcano plot showing the difference in the relative abundance of Dorea between participants in the highest quartile of weight loss and those in the lowest at baseline. Baseline Dorea abundances were significantly higher among participants in the lowest quartile of weight loss. b Baseline Dorea abundances rather than Prevotella-to-Bacteroides ratio or gut microbiota richness was predictive of post-intervention weight loss. AUROC showing how the aforementioned parameters were predictive of weight loss. c The relative abundance of Dorea at baseline was positively associated with weight loss, i.e., a higher abundance corresponds to a lower amount of weight loss. A scatter plot showing the association between the relative abundance of Dorea at baseline and weight loss after 12 weeks. Additional file 6: Source data 5