Skip to main content

Table 1 Demographic information of the included cohorts

From: A neurodegenerative disease landscape of rare mutations in Colombia due to founder effects

Cohort

n

AAO

Female

APOE genotype no. (%)

ϵ2/ϵ2

ϵ2/ϵ3

ϵ2/ϵ4

ϵ3/ϵ3

ϵ3/ϵ4

ϵ4/ϵ4

Mean

Range

n

%

n

%

n

%

n

%

n

%

n

%

n

%

AD

376

59

30-90

249

66.2

-

-

15

4

4

1.1

168

45

139

37.1

49

13.1

FTLD-MND

197

58.8

21-82

92

46.7

1

0.5

18

9.1

-

-

122

62

49

24.9

7

3.6

EOD

73

54.5

25-75

49

67.1

-

-

2

2.7

-

-

39

53

20

27.4

12

16.4

Healthy

254

60

18-100a

159

62.6

2

0.8

25

9.8

1

0.4

159

45

61

23.9

4

1.6

 

549

60.7

3

0.3

60

6.7

5

0.6

488

54.2

269

29.9

72

8

  1. AD Alzheimer’s disease, FTLD-MND frontotemporal lobar degeneration and motor neuron disorder, EOD early-onset dementia not otherwise specified, AAO age at onset
  2. a Age at evaluation. There were three Individuals with uncalled APOE genotype (one from AD cohort and two healthy individuals)