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Fig. 3 | Genome Medicine

Fig. 3

From: Integration of genetic colocalizations with physiological and pharmacological perturbations identifies cardiometabolic disease genes

Fig. 3

Post-colocalization follow-up identifies various patterns of shared colocalization across tissues and traits. a Unique genes colocalizing with T2D (in any of the 4 studies), fasting insulin, or fasting glucose GWAS at selected loci (each row represents one locus). Adipose (S), subcutaneous adipose; adipose (V), visceral adipose. b LocusCompare plots illustrating an adipose-specific colocalization in PLEKHA1 (TAPP1). c LocusCompare plots illustrating an sQTL-specific colocalization for BDNF-AS. The eQTL association signal for another nearby gene, LIN7C, is shown for comparison

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Genome Medicine

ISSN: 1756-994X

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