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Fig. 3 | Genome Medicine

Fig. 3

From: Integrated analysis of single-cell and bulk RNA sequencing data reveals a pan-cancer stemness signature predicting immunotherapy response

Fig. 3

Analysis of the potential links between Stem.Sig and immune resistance using pan-cancer TCGA cohort. A Circos plot depicting the correlation between Stem.Sig and the expression level of immune-related genes across multiple cancer types. From inside to outside of the circos plot, the vertical axis with a black arrow indicated different cancer types, which were annotated by the y axis of plot B. B Heatmap depicting the correlation between Stem.Sig and the infiltration of immune cells across multiple cancer types. C Heatmap depicting the correlation between Stem.Sig and the Top 10 Hallmark pathways. D Correlation of median Stem.Sig and median TMB of each cancer type. E Correlation of median Stem.Sig and median ITH of each cancer type. GSVA scores were calculated to estimate the expression level of Stem.Sig for each sample

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