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Fig. 5 | Genome Medicine

Fig. 5

From: Integrated analysis of single-cell and bulk RNA sequencing data reveals a pan-cancer stemness signature predicting immunotherapy response

Fig. 5

Comparing AUC of Stem.Sig with other predictive gene signatures. A Circos plot depicting the performance of pan-cancer signatures in the testing set. The vertical axis indicated AUC values. Testing set comprises five different cohorts, including Hugo 2020 SKCM, Van Allen 2015 SKCM, Kim 2018 GC, Zhao 2019 GBM, Synder 2017 UC. B Heatmap comparing the predictive value of Stem.Sig and other pan-cancer signatures. Different signature rows were ordered by their AUC in the testing set. From top to bottom, Stem.Sig ranked first while Cytotoxic.Sig ranked last. C Bar plot depicting the AUC values of Stem.Sig and other melanoma-specific signatures in the SKCM cohort (Hugo 2016 + Van Allen 2015).

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Genome Medicine

ISSN: 1756-994X

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