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Fig. 2 | Genome Medicine

Fig. 2

From: Single-cell profiling of human dura and meningioma reveals cellular meningeal landscape and insights into meningioma immune response

Fig. 2

Immune cell composition of human dura consists of functionally diverse lymphoid and myeloid cell types. A UMAP visualization of immune cells identified by cell type (C1: naive/central memory T (TCM) cells; C5, C6: CD4+ effector memory T (TEM) cells; C2: CD8+ TEM cells; C11: resident memory T (TRM) cells; C3: CD8+ cytotoxic T cells (CTLs)). B Dot plot of gene expression of select cell type gene markers. C, D UMAP visualization of select lymphoid and myeloid marker gene expression. E UMAP visualization of dura DCs (C0, C1, C3, C4, C6, C7: DC-like; C2, C5, C8: migDC-like). F Expression heatmap of top 10 genes of top 10 principal components with hierarchical clustering and associated functional enrichment analysis of gene clusters

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