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Fig. 7 | Genome Medicine

Fig. 7

From: Single-cell profiling of human dura and meningioma reveals cellular meningeal landscape and insights into meningioma immune response

Fig. 7

Analysis of meningioma cells reveals subclonal tumor populations with varying chromosomal abnormalities. A UMAP visualization of one paired dura and meningioma sample and two additional meningioma samples. B UMAP visualization of predicted tumor cells from MEN104, MEN105, and MEN09 samples. C Top 10 DEGs expressed in >50% cells of each sample-specific tumor cluster. D-F UMAP visualization of each individual sample-specific tumor cluster with unsupervised clustering and highlighted by respective CNV group (CG#) identities. G–I Expression heatmaps of the top 10 genes of the top 10 principal components of sample-specific tumor cells (D-F) with hierarchical clustering and associated functional enrichment analysis of gene clusters

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Genome Medicine

ISSN: 1756-994X

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