Fig. 1
From: Rapid molecular diagnostics of tuberculosis resistance by targeted stool sequencing
Study flow chart demonstrating results classified in accordance with real-time polymerase chain reaction (qPCR) and concentrations in fg/μl (1 and 100 fg/uL of DNA equates to 62.65 CFU and 2316.13 CFU of H37Rv Mtb/50 mg of stool). Targeted sequencing quality was graded as quality (ND) not detected (red), quality – indicative of partial reads (yellow), and quality + , +  + , and +  +  + indicating complete reads with adequate depth of coverage (green). A Cohort 1 and (B) Cohort 2. *partial resistance report possible for one sample. Abbreviations: ND, not detected