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Fig. 3 | Genome Medicine

Fig. 3

From: Combined exome and transcriptome sequencing of non-muscle-invasive bladder cancer: associations between genomic changes, expression subtypes, and clinical outcomes

Fig. 3

Univariate survival analysis. Kaplan-Meier plots comparing the progression-free survival (PFS; progression to MIBC) with different indices of genomic alteration: tumour mutational burden (TMB), copy number burden (CNB), APOBEC enrichment, and homologous recombination deficiency (HRD). The top row is when considering all NMIBCs (n = 93) in the BCPP cohort, and the bottom row is considering G3pT1 patients only (n = 51). For each of the genomic alteration indices, patients were divided into “high” and “low” based on being >/< than the median value, respectively. In addition to the log-rank test p-value, multiple testing correction p-values are also provided on the plot

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Genome Medicine

ISSN: 1756-994X

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