Fig. 4From: Comprehensive genomic and tumour immune profiling reveals potential therapeutic targets in malignant pleural mesotheliomaNeoantigen load derived from SNV and indel mutations in MPM. Predicted total neoantigen load derived from SNVs and indels with IC50 ≤ 500 nM in the A Creaney et al. cell line, pleura and pleural effusion samples and B TCGA pleura samples. Pearson correlation plots between short nucleotide variants (SNVs) on x-axis and neoantigen load on y-axis for C Creaney et al. and D TCGA dataset. E Boxplots for predicted total neoantigen load (IC50 ≤ 500 nM) (y-axis) in Creaney et al. cell line, pleura and pleural effusion samples and TCGA pleura samples (x-axis). F Boxplots for expressed neoantigen load (IC50 ≤ 500 nM) in Creaney et al. samples and TCGA pleural samples. p-values shown are from Wilcox testBack to article page