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Fig. 1 | Genome Medicine

Fig. 1

From: Acetyl-CoA metabolism drives epigenome change and contributes to carcinogenesis risk in fatty liver disease

Fig. 1

A Histone acetylation and γH2AX levels in livers of control and high-fructose diet mice. B Histone acetylation and γH2AX levels in livers of control and high-fat diet rats. Ci Lipid content of IHH cells cultured in control or oleic acid-supplemented media. Cii Representative fluorescence microscopy image of IHH cells cultured in control or oleic acid-supplemented media (blue nuclear stain and green lipid stain). D Nuclear area measurement of IHH cells cultured in control or oleic acid-supplemented media after DNAse I treatment. Error bars are ± SEM. Histone westerns all groups n = 4, Lipidtox assay n = 7/8, DNaseI Assay n = 3. *P < 0.05, ***P < 0.001 in t-test

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Genome Medicine

ISSN: 1756-994X

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