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Fig. 4 | Genome Medicine

Fig. 4

From: Acetyl-CoA metabolism drives epigenome change and contributes to carcinogenesis risk in fatty liver disease

Fig. 4

ChIP-qPCR analyses ɣH2AX and H4K16ac levels at PTEN (Ai), TP53 (Aii) and TERT promoter (Aiii) in IHH cells cultured in control media, oleic acid or oleic acid plus inhibitor drugs. Error bars are ± SEM. All treatments n = 3. #,*P < 0.05, ###P < 0.0001 in 1-way ANOVA, * H4K16ac and # ɣH2AX. B ChIP-qPCR analyses ɣH2AX at TP53 and TERT promoter in 3 samples from one human healthy liver and one human fatty liver

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Genome Medicine

ISSN: 1756-994X

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