Table 1 Characteristics of MDR and pre-XDR/XDR cases with factors associated with pre-XDR/XDR-TB based on univariate and multivariate analysis

Total

268

100%

748

100%

Gender

 M

114

43%

320

43%

1.00

0.75

1.35

1

 F

153

57%

428

57%

 Unknown

1

0%

0

0%

Age

  < 18

37

14%

93

12%

0.89

0.58

1.38

0.59

 18–40

168

63%

489

65%

1.12

0.83

1.52

0.46

 40–60

45

17%

138

18%

1.12

0.77

1.66

0.58

  > 60

17

6%

29

4%

0.6

0.31

1.18

0.12

 Unknown

1

0%

0

0%

Lineage

 Lineage 1 (EAI)

37

14%

13

2%

0.11

0.05

0.22

 < 0.001

0.19

0.09

0.41

 < 0.001

 Lineage 2 (Beijing)

121

45%

592

79%

4.60

3.38

6.28

 < 0.001

2.09

1.26

3.45

 < 0.01

 Lineage 3 (Delhi-CAS)

70

26%

69

9%

0.29

0.20

0.42

 < 0.001

0.54

0.32

0.89

0.02

 Lineage 4 (Euro-American)

40

15%

74

10%

0.63

0.41

0.97

0.03

 M. bovis

0

0%

0

0%

Clustering

 Yes

155

58%

591

79%

2.74

2.01

3.74

 < 0.001

0.92

0.62

1.35

0.66

 No

113

42%

157

21%

Cluster

 Cluster 1

44

16%

213

28%

2.03

1.40

2.98

 < 0.001

1.19

0.74

1.91

0.46

 Cluster 2

12

4%

115

15%

3.87

2.09

7.85

 < 0.001

2.36

1.19

4.69

0.01

 Cluster 3

16

6%

71

9%

1.65

0.93

3.10

0.09

1.09

0.58

2.08

0.79