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Fig. 3 | Genome Medicine

Fig. 3

From: Single-cell multimodal analysis identifies common regulatory programs in synovial fibroblasts of rheumatoid arthritis patients and modeled TNF-driven arthritis

Fig. 3

Sub-clustering analysis of S4a SFs revealed a homeostatic and an inflammatory state of LSFs. A UMAP representation of the identified lining sub-clusters. Cells belonging to the homeostatic group (hS4a) are colored in blue, while cells belonging to the inflammatory group (iS4a) are colored in red. C Barplot showing the relative abundances of cells in each sub-cluster in healthy conditions and during disease progression. C Feature plots of selected genes showing differential patterns of expression in the two sub-clusters. D Dot plot of shared and specific enriched GO biological processes in the two sub-clusters.

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Genome Medicine

ISSN: 1756-994X

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