Skip to main content

Table 2 Multivariate Cox analyses of cancer-specific survival in 237 patients of the validation cohort (C5) with \({P}_{psa}<0.05\) and all clinicopathological parameters available

From: A novel molecular signature identifies mixed subtypes in renal cell carcinoma with poor prognosis and independent response to immunotherapy

Variable Level Hazard ratio (95% CI) P-value
Sex
  Female 1  
Male 0.88 (0.46–1.70) 0.71
Age, years
  Linear 0.99 (0.97–1.02) 0.59
T
  1 1  
2 1.83 (0.4–8.43) 0.44
3 5.12 (2.1–12.51) 3.4E − 04
4 11.49 (2.54–51.88) 1.5E − 03
N
  0 1  
1/2 1.62 (0.73–3.62) 0.24
X 0.53 (0.14–1.96) 0.34
M
  0 1  
1 6.06 (2.74–13.41) 8.7E − 06
X 1.45 (0.32–6.51) 0.63
Tumor size, cm
  Linear 0.92 (0.83–1.02) 9.7E − 02
Histology
  ccRCC 1  
pRCC 2 (0.96–4.16) 6.2E − 02
chRCC 8.8 (0.86–89.78) 6.7E − 02
Mixed 1.88 (0.28–12.67) 0.52
PI5 (RCC-R score)
  Linear 2.14 (1.14–4.04) 1.8E − 02