Fig. 2
From: African-specific alleles modify risk for asthma at the 17q12-q21 locus in African Americans
17q12-q21 haplotypes in whole-genome sequences from individuals with asthma and homozygous for the 5-SNP haplotype. A Bar graph of haplotypes present in 44 Europeans (88 chromosomes) and 177 African Americans (354 chromosomes). The allelic composition and color code of each 5-SNP haplotype are shown under the bars. The purple star designates the African American high-risk haplotype 4. B ChromoPainter display of the haplotypes (88 chromosomes) in European Americans. C ChromoPainter display of 89 randomly selected chromosomes from the 354 chromosomes in African Americans. All chromosomes are shown in Additional file 1: Fig. S3. The LD plots include 17 SNPs previously associated with asthma in GWAS or with expression of genes at this extended locus, as previously described [11], are shown below the ChromoPainter displays. LD data are from 1000 Genomes (CEU and ASW, respectively); r2 values are shown in each diamond. The darker the diamond, the more LD; black diamonds are r2 = 1.0