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Table 1 Whole-genome sequence datasets

From: African-specific alleles modify risk for asthma at the 17q12-q21 locus in African Americans

Study

Race/ethnicity

Sample sizes

dbGaP accession number

 

Total sample

Asthma cases

Cases homozygous for a 5-SNP haplotype

Reference

URECA

African American

329

176

36

phs002921.v1.p1

[33]

APIC

African American

321

321

87

phs002921.v1.p1

[32]

CAAPA

African American

320

168

40

phs001123.v2.p1

[30]

EVE

African American

90

90

14

phs001156.v2.pa

[28]

EVE

European American

100

100

44

phs001156.v2.p1

[28]

  1. URECA Urban Environment and Childhood Asthma, APIC Asthma Phenotypes in Inner-City Children, CAAPA Consortium on Asthma among African-Ancestry Populations in the Americas
  2. See “Methods” for descriptions of each cohort