Table 2 Location and frequencies of the nine novel African-specific SNPs in the full sample
From: African-specific alleles modify risk for asthma at the 17q12-q21 locus in African Americans
rsID | Variant | Position (hg38) | Location | EA_Hap1 (2n=69) | EA_Hap2 (2n=118) | AA_Hap1 (2n=212) | AA_Hap2 (2n=891) | AA_Hap3 (2n=408) | AA_Hap4 (2n=386) | AA_Hap4 Asthmatic, Homozygotes (2n=36) |
|---|---|---|---|---|---|---|---|---|---|---|
rs150276395 | G->A | chr17:39908449 | GSDMB intron 6 | 0 | 0 | 0.024 | 0.039 | 0.042 | 0.53 | 0.78 |
rs8065520 | T->C | chr17:39915395 | GSDMB intron 2 | 0 | 0 | 0.066 | 0.094 | 0.270 | 0.79 | 0.97 |
rs73985226 | A->G | chr17:39920081 | Intergenic | 0 | 0 | 0.024 | 0.037 | 0.029 | 0.50 | 0.78 |
rs73985227 | G->A | chr17:39921437 | ORMDL3 3’UTR | 0 | 0 | 0.024 | 0.038 | 0.032 | 0.52 | 0.78 |
rs28623237 | T->C | chr17:39924694 | ORMDL3 intron 3 | 0 | 0 | 0.033 | 0.062 | 0.037 | 0.76 | 0.94 |
rs73985229 | G->A | chr17:39925400 | ORMDL3 intron 1 | 0 | 0 | 0.019 | 0.039 | 0.029 | 0.53 | 0.78 |
rs113282230 | A->T | chr17:39927157 | ORMDL3 intron 1 | 0 | 0 | 0.019 | 0.039 | 0.029 | 0.53 | 0.78 |
rs113571956 | A->T | chr17:39927234 | ORMDL3 intron 1 | 0 | 0 | 0.019 | 0.039 | 0.029 | 0.53 | 0.78 |
rs73985230 | T->C | chr17:39929476 | Intergenic | 0 | 0 | 0.019 | 0.039 | 0.027 | 0.50 | 0.75 |