Table 4 Sensitivity (detection of CIN3+) of the WID-CIN test at different levels of specificity and age groups in the predictive validation set

Specificity at 50%

All ages

−0.70

74.3% (68.4–80.2) [156/210]

< 30 years

−0.59

61.4% (51.9–70.9) [62/101]

≥ 30 years

−0.75

80.7% (73.3–88.1) [88/109]

Specificity at 75%

All ages

−0.52

54.8% (48.0–61.5) [115/210]

< 30 years

−0.45

53.5% (43.7–63.2) [54/101]

≥ 30 years

−0.60

56.9% (47.6–66.2) [62/109]

Specificity at 90%

All ages

−0.33

36.7% (30.1–43.2) [77/210]

< 30 years

−0.26

29.7% (20.8–38.6) [30/101]

≥ 30 years

−0.46

42.2% (32.9–51.5) [46/109]