CTpathway: a CrossTalk-based pathway enrichment analysis method for cancer research

Table 3 Top 10 significant pathways identified by CTpathway based on the GSE116959 LUAD data set

ID	Pathway name	#Node	PS	P-value	FDR	D^a	G^a	G^a	P^a	L^a
hsa05200	Pathways in cancer	454	0.187	1.37×10⁻⁸	2.52×10⁻⁶	√		√	√
hsa05152	Tuberculosis	175	0.164	1.69×10⁻⁸	2.52×10⁻⁶		√			√
hsa05140	Leishmaniasis	72	0.233	2.58×10⁻⁸	2.57×10⁻⁶	√	√	√	√	√
hsa05133	Pertussis	52	0.239	1.03×10⁻⁷	3.09×10⁻⁶	√	√	√		√
hsa04110	Cell cycle	124	0.237	6.88×10⁻⁸	3.09×10⁻⁶	√	√	√	√
hsa04510	Focal adhesion	199	0.201	4.49×10⁻⁸	3.09×10⁻⁶	√
hsa05166	Human T-cell leukemia virus 1 infection	233	0.196	9.77×10⁻⁸	3.09×10⁻⁶	√				√
hsa04512	Ascorbate and ECM-receptor interaction	81	0.181	8.56×10⁻⁸	3.09×10⁻⁶	√				√
hsa04610	Complement and coagulation cascades	55	0.171	8.71×10⁻⁸	3.09×10⁻⁶	√		√	√	√
hsa05150	Staphylococcus aureus infection	39	0.171	8.20×10⁻⁸	3.09×10⁻⁶	√	√			√

ISSN: 1756-994X