Table 4 Top 10 significant pathways only identified by CTpathway based on the GSE9891 OV data set
From: CTpathway: a CrossTalk-based pathway enrichment analysis method for cancer research
ID | Pathway name | #Node | PS | P-value | FDR | DEG proportion |
|---|---|---|---|---|---|---|
hsa04072 | Phospholipase D signaling pathway | 118 | 0.096 | 1.44×10−7 | 1.65×10−6 | 0.025 |
hsa04010 | MAPK signaling pathway | 295 | 0.085 | 3.14×10−7 | 2.47×10−6 | 0.014 |
hsa04550 | Signaling pathways regulating pluripotency of stem cells | 109 | 0.109 | 7.30×10−7 | 5.08×10−6 | 0.037 |
hsa04310 | Wnt signaling pathway | 144 | 0.096 | 1.45×10−6 | 8.85×10−6 | 0.028 |
hsa05202 | Transcriptional misregulation in cancer | 19 | 0.140 | 1.85×10−6 | 1.11×10−5 | 0.053 |
hsa05212 | Pancreatic cancer | 75 | 0.126 | 2.60×10−6 | 1.49×10−5 | 0 |
hsa01521 | EGFR tyrosine kinase inhibitor resistance | 79 | 0.113 | 4.28×10−6 | 2.35×10−5 | 0.038 |
hsa05225 | Hepatocellular carcinoma | 168 | 0.093 | 9.76×10−6 | 5.12×10−5 | 0.006 |
hsa04390 | Hippo signaling pathway | 153 | 0.090 | 1.15×10−5 | 5.85×10−5 | 0.032 |
hsa05224 | Breast cancer | 145 | 0.096 | 3.42×10−5 | 1.49×10−4 | 0.014 |