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Fig. 1 | Genome Medicine

Fig. 1

From: Neutrophil extracellular traps have auto-catabolic activity and produce mononucleosome-associated circulating DNA

Fig. 1

Schematic overview of the in vitro, ex vivo, and in vivo studies of cirDNA production by NET. A In vitro study of gHMW DNA degradation in blood fluids using Y chromosome analysis. B Ex vivo study of NET production and degradation using Y chromosome analysis. C In vitro study of the effect of NE/MPO on cfDNA size profile using Y chromosome analysis. D In vivo study of the effect of NE on cirDNA topology. E In vivo study of NET-associated disorders

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Genome Medicine

ISSN: 1756-994X

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