Skip to main content
Fig. 2 | Genome Medicine

Fig. 2

From: Genomic and transcriptomic analysis of a diffuse pleural mesothelioma patient-derived xenograft library

Fig. 2

Comparative immunohistochemistry and next generation sequencing of patient samples and PDX models. A Concordance of IHC markers between PDX and patient samples. BAP1 concordance was defined as loss/retained. WT1, mesothelin, VISTA, and PD-L1 concordance was defined as the PDX and patient sample expression being within ±25% expression of each other. B Genomic landscape of patients’ samples (n = 19), C PDX samples (n = 22), and D paired patient/PDX samples (n = 19) with available material using MSK-IMPACT targeted next generation sequencing. Genes were annotated if noted to have at least one alteration in the patient cohort

Back to article page

Genome Medicine

ISSN: 1756-994X

Contact us