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Fig. 4 | Genome Medicine

Fig. 4

From: Genomic and transcriptomic analysis of a diffuse pleural mesothelioma patient-derived xenograft library

Fig. 4

Gene expression changes in mesothelioma PDX models grouped by platinum doublet and clinical outcomes in the contributing patients. A Heatmap of gene expression of PDX samples for top genes altered by PFS on platinum doublet (< 6 months vs ≥ 6 months). B Pathway enrichment analyses of the top pathways altered by platinum doublet PFS (< 6 months vs ≥ 6 months) in PDXs. C Heatmap of gene expression of PDX samples for top genes altered between OS (< 2 years vs ≥ 2 years). D Pathway enrichment analyses of the top pathways altered between OS (< 2 years vs ≥ 2 years)

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