Fig. 5

Gene expression changes in mesothelioma PDX models grouped by platinum/pemetrexed exposure at the time of PDX sample collection and OncoCast-DPM risk score. A Heatmap of gene expression of PDX samples for top genes altered by exposure to platinum/pemetrexed at the time of PDX sample collection. B Pathway enrichment analyses of the top pathways altered by exposure to platinum/pemetrexed vs untreated at the time of PDX sample collection. C Heatmap of gene expression of PDX samples for top 50 genes altered between OncoCast-MPM high vs low risk groups. D Pathway enrichment analyses of the top pathways altered between OncoCast-MPM high vs low risk