Fig. 1From: Whole-exome sequencing identifies novel protein-altering variants associated with serum apolipoprotein and lipid concentrationsFlowchart of the study design. PTVs: protein-truncating variants, i.e., exon loss, frameshift, stop or start gained or lost, splice acceptor, and donor variants. PAVs: protein-altering variants, defined as PTV plus missense variants, inframe insertions, and deletions. T1D, type 1 diabetes. GLGC: Global Lipids Genetics Consortium. UKBB: UK Biobank. CAD, coronary artery disease. MI, myocardial infarctionBack to article page