Fig. 2From: Therapy sculpts the complex interplay between cancer and the immune system during tumour evolutionTherapy induced immunogenicity. Chemotherapy and radiotherapy may lead to the generation of neoantigens via DNA damage which may increase the immunogenicity of a cell. Checkpoint blockage and cancer vaccines do not alter the DNA but may lead to the activation of T cells and to increased neoantigen presentation to T cells respectivelyBack to article page