Fig. 1From: CRAG: de novo characterization of cell-free DNA fragmentation hotspots in plasma whole-genome sequencingThe schematic of the CRAG approach. a The schematic of using cfDNA hotspots for the cancer diagnosis. b The schematic of cfDNA hotspot identification. c The Q–Q plot for the negative binomial modeling of IFS score distribution. d The distribution of IFS around the hotspots (BH01, healthy)Back to article page