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Fig. 2 | Genome Medicine

Fig. 2

From: Calculating variant penetrance from family history of disease and average family size in population-scale data

Fig. 2

Example interface and output of the ADPenetrance web tool [20]. Legend: Here we show the example of penetrance of SOD1 variants for amyotrophic lateral sclerosis in a European population, applying variant frequency estimates for familial and sporadic ALS patients of European ancestry, an estimate of ALS disease risk among people not harbouring SOD1 variants, and the average Total Fertility Rate for the European Union in 2018 [22, 35]

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Genome Medicine

ISSN: 1756-994X

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