Fig. 2

Shared features of human and experimental DN. a Heatmap displaying the Pearson correlation coefficient between scRNA-seq and bulk RNA-seq data. b Overview of significant glomerular DEGs detected in both single-cell and bulk RNA-seq datasets, as well as in the ERCB patient dataset. cHeatmap showing the significant regulation of DEGs identified in microdissected glomeruli and in glomerular cells from DN patients and mice, respectively. Nonsignificant genes are shown in grey. ERCB, European Renal cDNA Bank