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Fig. 5 | Genome Medicine

Fig. 5

From: Single-cell transcriptomics reveals a mechanosensitive injury signaling pathway in early diabetic nephropathy

Fig. 5

Immunofluorescence staining confirms the activation of MRTFB in mesangial cells during early DN. Immunofluorescence staining of the human kidney samples (ctrl: n = 2, DN: n = 5). Representative images showing the expression and localization of MRTFA and MRTFB in control and DN glomeruli. Glomerular endothelial cells were labeled by CD34, podocytes were labeled by NPHS1 (Nephrin), and nuclei were counterstained with HOECHST. Arrows indicate mesangial cells, which were negative for CD34 and NPHS1

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