Fig. 5

Core genome SNP-based phylogeny of all ST-131 E. coli isolates in our dataset (n=275). Labels for clades A, B, B0, C0, C2, and C1 are indicated and are colored purple, green, light green, light blue, blue, and dark blue, respectively. Metadata are represented as rings from inner to outer: variations in the fimH gene, presence of point mutations in gyrA and parC (filled yellow square), fluoroquinolone (ciprofloxacin and/or levofloxacin) non-susceptibility (closed orange square), presence of ESBL gene (closed blue square), and multidrug-resistant isolate (red closed square). Non-typeable fimH alleles due to truncation or missing gene were grouped with other rare variants identified (Additional file 1: Table S1)