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Fig. 4 | Genome Medicine

Fig. 4

From: Neutralization sensitivity, fusogenicity, and infectivity of Omicron subvariants

Fig. 4

SARS-CoV-2 S-based cell fusion assay. a Merged images of mNeonGreen fluorescence and tdTomato red fluorescence 6 h after co-culturing. The number of nuclei (green) in a syncytium (red) represents how many cells fused to one. b, c The relative fusion levels of spike variants mediated cell fusion based on luciferase activity (b) and heatmap showing p values from pairwise comparisons of the relative fusion levels of two spike variants (c). d Representative western blots of spike variants expression. β-Actin was used as an internal control. A two-tailed Kruskal–Wallis test with a false discovery rate for multiple comparisons

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