Fig. 2
Regional Plot the FMNL3 Gene on Chromosome 12. Regional plots for the breast cancer association of FMNL3 at 12q13.12. A Depiction of coding regions of all coding genes (data retrieved from Ensembl biomart hg38) within the chromosomal region with FMNL3 highlighted in blue. B Variants included in the aggregation test, plotted according to their chromosomal position and analysis weight. Highlighted in blue are variants exclusively present in the analysis of samples of diverse ancestry. C Single-marker association results based on the same samples [10], with blue solid line denoting P-value for meta-analysis of all cohorts for gene of interest (P = 1.24 × 10−5) in this study and blue dashed line denoting unadjusted P-value for all-European meta-analysis (P = 6.11 × 10−6)