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Fig. 2 | Genome Medicine

Fig. 2

From: Risk assessment for colorectal cancer via polygenic risk score and lifestyle exposure: a large-scale association study of East Asian and European populations

Fig. 2

The cumulative risk of developing colorectal cancer according to the PRS and lifestyle score in the UK Biobank cohort. A Cumulative incidence of colorectal cancer in the low, intermediate, and high PRS groups. B Cumulative incidence of colorectal cancer in unfavorable, intermediate, and favorable lifestyle groups. C Cumulative incidence of colorectal cancer stratified by different levels of PRS and lifestyle score. D The associations of PRS and lifestyle score with incident colorectal cancer. The HR and 95% CI were derived from the Cox regression model with the adjustment of sex, age, center, and first 10 principal components. PRS, polygenic risk score; HR, hazard ratio; 95% CI, 95% confidence intervals

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Genome Medicine

ISSN: 1756-994X

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