Locus | Chr | SNP | Positiona | Alleleb | RAFc | OR (95% CI)d | Pd | Phete | |
---|---|---|---|---|---|---|---|---|---|
EAS | EUR | ||||||||
1q25.3 | 1 | rs6424881 | 182986765 | C/T | 0.482 | 0.587 | 1.08 (1.06, 1.10) | 3.05E−14 | 0.530 |
1q41 | 1 | rs12140604 | 222159150 | G/C | 0.204 | 0.223 | 1.09 (1.07, 1.12) | 3.49E−14 | 0.145 |
3p14.1 | 3 | rs7623129 | 64624426 | C/T | 0.455 | 0.534 | 1.06 (1.04, 1.08) | 2.68E−08 | 0.714 |
3q13.2 | 3 | rs72942485 | 112999560 | G/A | 0.948 | 0.991 | 1.16 (1.11, 1.23) | 4.47E−09 | 0.639 |
3q22.2 | 3 | rs58383609 | 133735742 | C/A | 0.592 | 0.853 | 1.07 (1.05, 1.10) | 1.54E−08 | 0.677 |
4q24 | 4 | rs1909122 | 106127004 | T/C | 0.453 | 0.645 | 1.09 (1.06, 1.12) | 2.79E−11 | 0.097 |
5p13.1 | 5 | rs72748467 | 40262840 | T/C | 0.042 | 0.245 | 1.09 (1.06, 1.12) | 7.91E−10 | 0.735 |
5q31.1 | 5 | rs519705 | 134462596 | G/A | 0.369 | 0.540 | 1.07 (1.05, 1.10) | 8.04E−12 | 0.001 |
5q31.1 | 5 | rs7729156 | 134507139 | T/C | 0.305 | 0.447 | 1.09 (1.06, 1.11) | 1.40E−15 | 0.411 |
5q32 | 5 | rs2302274 | 149546426 | G/A | 0.596 | 0.459 | 1.06 (1.04, 1.08) | 1.93E−09 | 0.839 |
6p21.33 | 6 | rs2071590 | 31539768 | G/A | 0.759 | 0.626 | 1.06 (1.04, 1.08) | 1.68E−08 | 0.033 |
7p12.3 | 7 | rs6948177 | 47510741 | G/A | 0.895 | 0.668 | 1.06 (1.04, 1.09) | 3.98E−08 | 0.932 |
7p13 | 7 | rs7810512 | 45150331 | A/C | 0.744 | 0.747 | 1.07 (1.05, 1.09) | 9.87E−09 | 0.301 |
8q23.3 | 8 | rs2450114 | 117623719 | A/G | 0.146 | 0.115 | 1.09 (1.06, 1.12) | 1.46E−08 | 0.003 |
8q23.3 | 8 | rs2015069 | 117639532 | T/C | 0.582 | 0.859 | 1.09 (1.06, 1.12) | 5.65E−12 | 0.458 |
8q23.3 | 8 | rs28668628 | 117679601 | C/T | 0.013 | 0.113 | 1.12 (1.07, 1.16) | 2.12E−08 | 0.629 |
8q24.21 | 8 | rs79122086 | 128397907 | G/T | 0.203 | 0.123 | 1.12 (1.08, 1.16) | 1.43E−08 | 0.009 |
8q24.21 | 8 | rs6470510 | 128429660 | T/C | 0.158 | 0.187 | 1.11 (1.09, 1.14) | 5.02E−17 | 0.032 |
9p21.3 | 9 | rs1537372 | 22103183 | G/T | 0.482 | 0.581 | 1.07 (1.05, 1.10) | 1.28E−12 | 0.104 |
10p14 | 10 | rs827385 | 8705799 | T/A | 0.635 | 0.632 | 1.10 (1.08, 1.12) | 7.23E−18 | 0.001 |
10q22.3 | 10 | rs704017 | 80819132 | G/A | 0.279 | 0.540 | 1.12 (1.08, 1.15) | 3.67E−13 | 0.597 |
10q24.2 | 10 | rs17578367 | 101344167 | A/G | 0.179 | 0.198 | 1.07 (1.05, 1.10) | 2.39E−08 | 0.887 |
10q25.2 | 10 | rs12241008 | 114280702 | C/T | 0.300 | 0.094 | 1.14 (1.11, 1.17) | 5.36E−21 | 0.683 |
10q25.2 | 10 | rs11196170 | 114722621 | A/G | 0.682 | 0.255 | 1.07 (1.04, 1.09) | 3.19E−08 | 0.013 |
11q12.2 | 11 | rs174598 | 61621194 | G/A | 0.432 | 0.643 | 1.06 (1.04, 1.09) | 2.27E−08 | 0.236 |
11q13.4 | 11 | rs11236148 | 74264335 | G/A | 0.923 | 0.915 | 1.10 (1.07, 1.14) | 3.52E−08 | 0.243 |
11q13.4 | 11 | rs4944913 | 74321349 | A/G | 0.680 | 0.662 | 1.08 (1.06, 1.11) | 2.17E−13 | 0.885 |
11q13.4 | 11 | rs6592590 | 74381029 | T/C | 0.352 | 0.406 | 1.06 (1.04, 1.08) | 4.57E−08 | 0.180 |
12p13.32 | 12 | rs3217840 | 4394877 | T/C | 0.963 | 0.604 | 1.08 (1.05, 1.10) | 1.50E−09 | 0.108 |
12q12 | 12 | rs908664 | 43133634 | C/A | 0.607 | 0.508 | 1.06 (1.04, 1.08) | 1.24E−09 | 0.700 |
12q13.12 | 12 | rs11169572 | 51216890 | C/T | 0.263 | 0.381 | 1.07 (1.05, 1.09) | 9.99E−11 | 0.285 |
12q24.21 | 12 | rs9634162 | 115098094 | A/G | 0.536 | 0.500 | 1.06 (1.04, 1.08) | 3.29E−08 | 0.625 |
14q22.1 | 14 | rs8023022 | 51366863 | T/C | 0.456 | 0.209 | 1.07 (1.05, 1.09) | 1.84E−09 | 0.727 |
14q22.2 | 14 | rs17563 | 54417522 | A/G | 0.714 | 0.430 | 1.06 (1.04, 1.08) | 9.30E−09 | 0.260 |
15q13.3 | 15 | rs1406389 | 33009478 | T/A | 0.716 | 0.209 | 1.12 (1.08, 1.15) | 1.32E−13 | 0.186 |
16q23.2 | 16 | rs12921341 | 80040583 | G/T | 0.590 | 0.468 | 1.06 (1.04, 1.08) | 4.43E−08 | 0.885 |
18q21.1 | 18 | rs6507874 | 46448805 | T/C | 0.310 | 0.530 | 1.15 (1.13, 1.18) | 2.66E−36 | 0.471 |
18q21.1 | 18 | rs2337107 | 46459323 | T/C | 0.328 | 0.464 | 1.08 (1.06, 1.10) | 1.82E−14 | 0.036 |
19q13.11 | 19 | rs73039434 | 33524919 | T/G | 0.799 | 0.945 | 1.11 (1.07, 1.15) | 1.16E−08 | 0.483 |
19q13.43 | 19 | rs2305122 | 59056752 | C/G | 0.057 | 0.230 | 1.10 (1.07, 1.13) | 4.66E−10 | 0.326 |
20p12.3 | 20 | rs355529 | 6374388 | T/A | 0.126 | 0.300 | 1.10 (1.08, 1.13) | 1.00E−15 | 0.186 |
20p12.3 | 20 | rs1015563 | 6690101 | T/C | 0.301 | 0.317 | 1.09 (1.06, 1.11) | 1.14E−14 | 0.710 |
20p12.3 | 20 | rs6086208 | 7765463 | T/C | 0.330 | 0.266 | 1.10 (1.07, 1.12) | 3.82E−17 | 0.015 |
20p12.3 | 20 | rs2294304 | 7877079 | A/G | 0.574 | 0.989 | 1.11 (1.08, 1.15) | 2.10E−10 | 0.521 |
20q13.13 | 20 | rs6066825 | 47340117 | A/G | 0.711 | 0.642 | 1.07 (1.05, 1.10) | 3.41E−11 | 0.758 |
20q13.13 | 20 | rs6063515 | 49056905 | G/A | 0.478 | 0.596 | 1.07 (1.05, 1.10) | 2.07E−08 | 0.438 |
20q13.13 | 20 | rs6067417 | 48983697 | C/T | 0.758 | 0.579 | 1.06 (1.04, 1.09) | 4.76E−09 | 0.117 |
20q13.33 | 20 | rs6121558 | 60961365 | T/C | 0.852 | 0.749 | 1.11 (1.08, 1.14) | 2.16E−13 | 0.186 |