Fig. 5

Comparison of the 166 genes mapped to 11 genomic risk loci with PTB and infant disease. a The 166 mapped genes were compared with 3 sets of reported PTB genes including dbPTB from Sheikh et al. [57] and Uzun et al. [58], PTB-merged from 5 resources [10], and PNAS-identified DEGs in 2019 [10] (see Additional file 1: Table S7). b A bar graph showing significantly enriched GO biological processes and KEGG pathways based on the 50 PTB marker genes (see Additional file 1: Table S7). c,d Heatmaps showing expression profiling and clusters of the PTB genes predicted from GWAS under maternal PTB (c) and PTB infant with BPD and sepsis (d). The gene expression data was extracted from the listed GSE accession numbers of NCBI/GEO