Skip to main content
Fig. 6 | Genome Medicine

Fig. 6

From: Ultra-low-coverage genome-wide association study—insights into gestational age using 17,844 embryo samples with preimplantation genetic testing

Fig. 6

Associated analysis of the PTB-related genes in maternal and infant subtypes. a A gene co-expression network merging maternal and infant PTB subtypes. b A gene co-expression network merging maternal PTB and BPD of preterm infant. In a and b, oval nodes represent PTB-related genes predicted from GWAS using the 1744 born embryo samples, rectangle nodes refer to the 50 top PTB markers summarized from previously studies (Additional file 1: Table S7), involving immune or inflammation (blue), apoptosis (yellow), angiogenesis (green), coagulation (purple), and other biological processes (gray). Co-expressive edges (the Pearson correlation p-value < 0.01) linking nodes represent maternal (red), infant (blue), and both maternal and infant (black). c A graphic summary to illustrate gestational age’s association with PTB, infant disease, and breast cancer

Back to article page

Genome Medicine

ISSN: 1756-994X

Contact us