Table 2 Cox proportional hazards output for GrimAgeAccel and bAgeAccel in the test datasets. Hazard ratios are presented per standard deviation of the GrimAgeAccel and bAgeAccel variables. Further details in Additional File 4: Table S11. Asterisk symbol (*) indicates the following: the FHS cohort used here was the same as the test set from the original GrimAge paper
From: Refining epigenetic prediction of chronological and biological age
Cohort | N | N deaths | GrimAgeAccel Hazard ratio (95% CI) | bAgeAccel Hazard ratio (95% CI) |
|---|---|---|---|---|
LBC193620,21 | 895 | 367 | 1.74 (1.57, 1.94) | 1.73 (1.56, 1.91) |
LBC192120,21 | 421 | 421 | 1.33 (1.20, 1.47) | 1.44 (1.29, 1.59) |
FHS*27,28 | 711 | 100 | 1.72 (1.35, 2.19) | 1.77 (1.40, 2.25) |
WHI B23 White30,31 | 998 | 418 | 1.44 (1.31, 1.58) | 1.45 (1.32, 1.60) |
WHI B23 Black30,31 | 676 | 229 | 1.35 (1.19, 1.53) | 1.42 (1.24, 1.62) |
WHI B23 Hispanic30,31 | 433 | 118 | 1.41 (1.18, 1.68) | 1.44 (1.21, 1.72) |