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Table 1 Baseline characteristics of study participants

From: Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19

 

Life-threatening COVID-19

Infected controls

P valuea

n = 3269

n = 1373

Sex, no. (%)

  

 < 0.0001

 Male

2314 (70.8%)

542 (39.5%)

 Female

955 (29.2%)

831 (60.5%)

Age (years)

 Mean (SD)

55.74 (17.40)

43.83 (20.14)

 < 0.0001

 Median (range)

57 (0.08–99)

43 (0.08–105)

 

Processing pipeline, no. (%)

  

 < 0.0001

 HGID laboratory

2492 (76.2%)

870 (63.4%)

 Other

777 (24.8%)

503 (36.6%)

Ancestry, no. (%)

  

 < 0.0001

 European

1374 (42.0%)

960 (69.9%)

 Middle Eastern

483 (14.8%)

158 (11.5%)

 Admixed American

466 (14.3%)

109 (7.9%)

 North African

300 (9.2%)

24 (1.7%)

 South Asian

279 (8.5%)

36 (2.6%)

 Sub-Saharan African

234 (7.1%)

43 (3.1%)

 East Asian

133 (4.1%)

43 (3.1%)

  1. HGID Human Genetics of Infectious Diseases
  2. aChi-squared tests were used to compare proportions, and t tests were used to compare the mean ages