Fig. 7
From: Stalled oligodendrocyte differentiation in IDH-mutant gliomas
Chromatin status of key members of myelination program and OPC specification and maintenance in IDH-mutant gliomas. A Chromatin status-based identification of cell populations and the chromatin status of canonical markers across the respective cell populations identified. t-SNE plots and heatmap are shown. B Inaccessible chromatin status of oligodendrocyte marker, myelin components, and myelination-regulatory genes in both proliferating and non-proliferating IDH-mutant glioma cells. C Open chromatin status in genes involved in OPC specification and maintenance in both proliferating and non-proliferating IDH-mutant glioma cells. IDH-mut: IDH-mutant, non-prolif: non-proliferating cells, prolif: proliferating cells, oligo: oligodendrocytes