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Fig. 8 | Genome Medicine

Fig. 8

From: Single-nucleus RNA sequencing of human pancreatic islets identifies novel gene sets and distinguishes β-cell subpopulations with dynamic transcriptome profiles

Fig. 8

Cellular processes identified by GSEA of the three β-cell sub-clusters β1, β2, and β3 in the in vivo snRNA-seq compared with the in vitro dataset. Dotplot depicting the expression levels and percentage of cells expressing four representatives. A ECM-related C2 pathway genes (interaction, response, organization, and integrins), B vesicle-related C2 pathway genes (biogenesis, budding, transport, lysosome), C insulin-related C2 pathway genes (processing, secretion and glucose metabolism), and D proliferation/differentiation related C2 pathway genes (proliferation, development, differentiation, regulation of gene expression) in the in vivo snRNA-seq compared with the in vitro dataset

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Genome Medicine

ISSN: 1756-994X

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