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Fig. 1 | Genome Medicine

Fig. 1

From: Genomic and transcriptomic features between primary and paired metastatic fumarate hydratase–deficient renal cell carcinoma

Fig. 1

The mutational landscape of paired primary and metastatic lesions of FH-RCC. A Integrated genomic and clinical data for 19 primary and matched metastatic lesions. B Percentage bar chart of presence of bone metastasis between patients with metastatic NF2 mutation and wild-type NF2. P-value was determined by Fisher’s exact test. C–G Paired ladder plots depict the changes of TMB, TNB, MSI, CNV burden, and WGII score in patient-matched cases. P-value was determined by Wilcoxon signed rank test. H,I Paired ladder plots depict the changes of WGII score in NF2 wild-type and NF2 mutated subgroups. P-value was determined by Wilcoxon signed rank test

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