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Fig. 2 | Genome Medicine

Fig. 2

From: Genomic and transcriptomic features between primary and paired metastatic fumarate hydratase–deficient renal cell carcinoma

Fig. 2

Clonality and phylogenetic trees of FH-RCC. A Evolutionary tree and clonal relationship between paired primary and metastasis. Cases were grouped into “synchronous” and “metachronous” metastasis. Metastasis and primary lesions shared clones were marked as red. The most recent common ancestor (MRCA) was denoted by the first node in the phylogenetic tree. B Summary of evolution pattern was displayed as fishplots. Patients with synchronous and metachronous metastasis were both featured as MRCA-dominated punctuated evolutionary pattern

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Genome Medicine

ISSN: 1756-994X

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