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Fig. 2 | Genome Medicine

Fig. 2

From: Sex differences in the polygenic architecture of hearing problems in adults

Fig. 2

Multi-tissue transcriptome-wide association study of hearing problems based on the sex-combined meta-analysis. The y-axis corresponds to two-tailed − log10 (p-value of the S-MultiXcan association). The x-axis reports the genes grouped based on the best single-tissue S-PrediXcan association. The red line refers to the Bonferroni multiple testing correction accounting for the number of genes tested (N = 22,335; p < 2.24 × 10.−6). Bold labels are reported for the top-10 Bonferroni significant association. Additional labels are included for the top significant result for each tissue. Detailed results are available in Additional file 1: Table S16

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