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Call for Papers - Translating the microbiome: health and disease

Guest Editor: Dr. Ramnik Xavier

New Content ItemResearch efforts exploring the human microbiome using large-scale metagenomics and multi-omics have rapidly expanded, facilitating characterization of microbiome composition, dynamics, variation, and function in health and disease. Such studies are increasing our understanding of the microbiome’s impact on the immune response and other physiological processes, and further enabling a shift from correlation to causation, with emerging insights into how this data can be utilized for diagnostic and therapeutic benefit. These efforts also highlight the need for the standardization of microbiome research protocols in order to accelerate progress through collaborative research. To capture advances in this growing area, Genome Medicine is pleased to announce a call for papers for our upcoming special issue on ‘Translating the microbiome: health and disease,' guest edited by Dr. Ramnik Xavier of the Broad Institute of MIT and Harvard

We are particularly interested in encouraging collaboration between basic and clinical researchers. The Guest Editor may be able to provide guidance on fostering such collaborations; please contact the editorial team to discuss further.

We are now inviting the submission of Research, Method, Software, Database and Guideline manuscripts of outstanding interest describing insights into all aspects of the human microbiome in health and disease including:

  ● Reference microbiomes
  ● Healthy microbiome
  ● Standards for microbiome analyses in basic and clinical research
  ● Trans-ethnic microbiome diversity 
  ● The maternal and developing microbiome
  ● Microbiome-immune homeostasis and regulation of the immune response
  ● Microbial biochemistry, metabolic dysregulation and diet
  ● Microbial metabolites in health and disease  
  ● Microbial genes, molecules, and function
  ● Gnotobiotic mice, synthetic microbial communities, and human translation 
  ● Host-microbiome interactions, dysbiosis
  ● Microbiome-encoded disease phenotypes
  ● Microbiome and cancer
  ● Microbiome in tumor immunity and therapeutic response 
  ● Gut-brain axis
  ● The human virome
  ● Antibiotics and the microbiome
  ● The microbiome and drug metabolism
  ● Metagenomics and integrative multi-omics 
  ● Microbiome analysis tools and technologies
  ● Microbiome diagnostics
  ● Precision editing/modulation of the microbiome 
  ● Translational interventions, clinical trials and therapies

Submission deadline extended: 31 January 2020

To submit your manuscript, please use the Genome Medicine online submission system and indicate in your covering letter that you would like the article to be considered for the ‘Translating the microbiome in health and disease’ special issue. If you would like to enquire about the suitability of a manuscript for consideration, please email

This collection of articles has not been sponsored and articles will undergo the journal’s standard peer-review process. The Guest Editor declares that they have no competing interests. The Guest Editor serves an advisory role to guide the scope of the special issue and commissioned content; final editorial decisions lie with the Editor.