Skip to content

Advertisement

Articles

Page 23 of 23

  1. Content type: Research

    Although microarray technology allows the investigation of the transcriptomic make-up of a tumor in one experiment, the transcriptome does not completely reflect the underlying biology due to alternative splic...

    Authors: Anneleen Daemen, Olivier Gevaert, Fabian Ojeda, Annelies Debucquoy, Johan AK Suykens, Christine Sempoux, Jean-Pascal Machiels, Karin Haustermans and Bart De Moor

    Citation: Genome Medicine 2009 1:39

    Published on:

  2. Content type: Musings

    Though the field has moved with glacial speed, gene therapies have been carried out successfully in patients with bone marrow disorders including immune deficiencies. The field may be poised to move forward mo...

    Authors: David G Nathan and Stuart H Orkin

    Citation: Genome Medicine 2009 1:38

    Published on:

  3. Content type: Review

    Alzheimer's disease is a progressive neurodegenerative disorder with high prevalence in old age. It is the most common cause of dementia, with a risk reaching 50% after the age of 85 years, and with the increa...

    Authors: Dimitrios Avramopoulos

    Citation: Genome Medicine 2009 1:34

    Published on:

  4. Content type: Review

    Functional genomic studies are dominated by transcriptomic approaches, in part reflecting the vast amount of information that can be obtained, the ability to amplify mRNA and the availability of commercially s...

    Authors: Julian L Griffin and Christine Des Rosiers

    Citation: Genome Medicine 2009 1:32

    Published on:

  5. Content type: Review

    Despite the recent success of genome-wide association studies (GWASs) in identifying loci consistently associated with coronary artery disease (CAD), a large proportion of the genetic components of CAD and its...

    Authors: Matthew B Lanktree and Robert A Hegele

    Citation: Genome Medicine 2009 1:28

    Published on:

  6. Content type: Commentary

    Disparities in health outcomes of members of different ancestral or ethnic groups can be observed in both developed and developing countries and continue to be a global concern. Genomic medicine can help towar...

    Authors: David Gurwitz and Jeantine E Lunshof

    Citation: Genome Medicine 2009 1:24

    Published on:

  7. Content type: Musings

    The wide general publication of a putative genetic test for athletic supremacy is clearly an abuse of genetics and reveals an undercurrent of hucksterism in biomedical science.

    Authors: David G Nathan and Stuart H Orkin

    Citation: Genome Medicine 2009 1:18

    Published on:

  8. Content type: Commentary

    The availability of personalized genomic tests, ordered directly by consumers, is rapidly growing. These tests are unlike other genetic or biochemical tests in the sheer amount of data they provide, but interp...

    Authors: David Magnus, Mildred K Cho and Robert Cook-Deegan

    Citation: Genome Medicine 2009 1:17

    Published on:

  9. Content type: Editorial

    The genome era in medicine is upon us. Questions that arise from patient and family care are a watershed for research and technology, which in turn fuel the cycle of opportunity for impact through delivery of ...

    Authors: Janet A Buchanan, Andrew R Carson, David Chitayat, David Malkin, M Stephen Meyn, Peter N Ray, Cheryl Shuman, Rosanna Weksberg and Stephen W Scherer

    Citation: Genome Medicine 2009 1:16

    Published on:

  10. Content type: Correspondence

    The Human Gene Mutation Database (HGMD®) is a comprehensive core collection of germline mutations in nuclear genes that underlie or are associated with human inherited disease. Here, we summarize the history of t...

    Authors: Peter D Stenson, Matthew Mort, Edward V Ball, Katy Howells, Andrew D Phillips, Nick ST Thomas and David N Cooper

    Citation: Genome Medicine 2009 1:13

    Published on:

  11. Content type: Minireview

    It has been established that heterozygous carriers of ataxia-telangiectasia-causing mutations in the ATM gene are at approximately two-fold higher risk of breast cancer. Several studies have attempted to assess t...

    Authors: Roger L Milne

    Citation: Genome Medicine 2009 1:12

    Published on:

  12. Content type: Review

    Genome medicine uses genomic information in the diagnosis of disease and in prescribing treatment. This transdisciplinary field brings together knowledge on the relationships between genetics, pathophysiology ...

    Authors: Aislyn D Wist, Seth I Berger and Ravi Iyengar

    Citation: Genome Medicine 2009 1:11

    Published on:

  13. Content type: Correspondence

    The use of race in biomedical research has, for decades, been a source of social controversy. However, recent events, such as the adoption of racially targeted pharmaceuticals, have raised the profile of the r...

    Authors: Timothy Caulfield, Stephanie M Fullerton, Sarah E Ali-Khan, Laura Arbour, Esteban G Burchard, Richard S Cooper, Billie-Jo Hardy, Simrat Harry, Robyn Hyde-Lay, Jonathan Kahn, Rick Kittles, Barbara A Koenig, Sandra SJ Lee, Michael Malinowski, Vardit Ravitsky, Pamela Sankar…

    Citation: Genome Medicine 2009 1:8

    Published on:

  14. Content type: Commentary

    The Genetic Information Nondiscrimination Act of 2008 (GINA) was recently enacted in the United States. Its supporters have applauded the passage of GINA, and they hope that it will alleviate public fear about...

    Authors: Amy L McGuire and Mary Anderlik Majumder

    Citation: Genome Medicine 2009 1:6

    Published on:

New Content Item

2017 Journal Metrics

Advertisement